Details for gene set MIXED, INCL. INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS, AND CARDIOFACIOCUTANEOUS SYNDROME[GSEA]

Table: GSEA Results Summary

Dataset	Chronic fatigue syndrome__20002-both_sexes-1482
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	MIXED, INCL. INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS, AND CARDIOFACIOCUTANEOUS SYNDROME
Enrichment Score (ES)	0.7581738
Normalized Enrichment Score (NES)	1.3099844
Nominal p-value	0.009
FDR q-value	0.14057629
FWER p-Value	0.354

Fig 1: Enrichment plot: MIXED, INCL. INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS, AND CARDIOFACIOCUTANEOUS SYNDROME
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	BRAF	149	2.541	0.1770	Yes
2	MAPK3	212	2.364	0.3459	Yes
3	RALGDS	413	2.017	0.4819	Yes
4	NF1	567	1.864	0.6093	Yes
5	SPRED1	1085	1.443	0.6857	Yes
6	RASA2	1423	1.250	0.7582	Yes
7	KRAS	3005	0.610	0.7148	No
8	HRAS	5149	0.293	0.6169	No
9	SOS1	5455	0.267	0.6194	No
10	RALBP1	6683	0.196	0.5654	No
11	RGL2	6756	0.193	0.5755	No
12	ARAF	8774	0.125	0.4724	No
13	SPRED2	8956	0.120	0.4711	No
14	TIAM1	9204	0.114	0.4657	No
15	MAP2K2	10544	0.087	0.3976	No
16	MRAS	11303	0.075	0.3608	No
17	RRAS	11904	0.065	0.3322	No
18	RASA1	12842	0.052	0.2839	No
19	NRAS	13928	0.037	0.2263	No
20	MAPK1	14894	-0.000	0.1726	No
21	RAP1A	15341	-0.000	0.1478	No
22	RAF1	15736	-0.000	0.1259	No
23	RRAS2	15771	-0.000	0.1240	No
24	RALB	16049	-0.000	0.1086	No
25	MAP2K1	16721	-0.000	0.0713	No

Fig 2: MIXED, INCL. INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS, AND CARDIOFACIOCUTANEOUS SYNDROME: Random ES distribution
Gene set null distribution of ES for MIXED, INCL. INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS, AND CARDIOFACIOCUTANEOUS SYNDROME